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Early-onset Cancer Rise Linked to Diet and Lifestyle

by | 4 October 2024

A global analysis undertaken in 2023 has revealed a concerning trend: the incidence of cancer diagnoses among adults under 50 has surged by 80% over the past three decades. This alarming pattern is echoed in the United Kingdom, where the increase stands at 25%. Researchers worldwide are delving into the potential causes, with many pointing to diet and lifestyle factors as significant contributors.

Diet and Lifestyle Under Scrutiny

Professor Charles Swanton, Chief Clinician at Cancer Research UK, highlights a growing body of research suggesting a connection between early-onset cancer and the consumption of ultra-processed foods. Speaking at the American Society of Clinical Oncology, Swanton noted that diets low in fibre and high in sugar might be fostering gut bacteria associated with early-onset colorectal cancer. These bacteria may induce specific mutations that undermine the body’s ability to prevent pre-cancerous cells from developing into tumours.

Complementing these findings, Dr Cathy Eng from Vanderbilt University Medical Centre in Nashville observed that many young cancer patients also suffer from lifestyle-related conditions, such as high blood pressure, high cholesterol, and diabetes, which are often linked to poor dietary habits.

Experts Urge Dietary Changes

Matthew Lambert, a nutritionist and health information and promotion manager at the World Cancer Research Fund (WCRF), advises reducing intake of ultra-processed foods. He points out that such foods, which include items like cakes, biscuits, pastries, crisps, sugar-sweetened drinks, and fast foods such as pizza and burgers, are typically low in fibre and essential nutrients. While it remains uncertain whether the risk associated with these foods lies in their composition or the tendency to overconsume them, the link between obesity and various cancers is well-established.

Professor Swanton has also warned of the dangers of regular consumption of red and processed meats like ham and bacon. Previous studies presented at the National Cancer Research Institute (NCRI) Cancer Conference have shown a 40% increased risk of bowel cancer in individuals who consume these meats daily. The risk is believed to be associated with nitrates in the meat, which combine with compounds in the body to damage cells.

Increasing Involvement of Younger Patients

In the United States, Dr Nicholas DeVito from Duke University in North Carolina reports a significant demographic shift, noting that the majority of his patients are now under 45. He attributes this change to the rise in ultra-processed food consumption, which constitutes about 75% of the U.S. diet. DeVito has called for more robust measures to protect the public from harmful food products, drawing parallels to successful anti-tobacco initiatives.

Dr DeVito emphasized, “Food can play a major role in prevention,” highlighting the importance of understanding how dietary choices impact cancer risk. A 2023 study published in Clinical Nutrition supports this view, finding a significant association between the intake of ultra-processed foods and an increased risk of various cancers, including colon, breast, and pancreatic cancers.

Broader Health Implications

The broader health implications of a diet high in ultra-processed foods extend beyond cancer. A meta-analysis indicates that such diets are linked to over 30 health conditions, including obesity, heart disease, and diabetes—all of which can heighten cancer risk. Addressing these concerns through education on healthier eating habits could potentially mitigate the rising cancer incidence among younger populations.

The Bottom Line

The surge in early-onset cancer diagnoses calls for a closer examination of contemporary dietary and lifestyle practices. While the research continues to evolve, current findings advocate for reducing the consumption of ultra-processed foods and adopting healthier dietary habits to combat the rising trend of cancer among younger adults.